An Assessment of Analgesic & Anti-inflammatory Activity Spondias mombin and Mapping of Variation of Potency under the Light Geographical Contrast Based Phenomenon
Tahmina Sharif Nila
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Maliha Rownak Ara Khan
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Najibah Nasrin
Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Isratul Jannat Mim
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Farhana Yesmin Peya
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Amatun Noor Prapty
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Lia Rose Merry D. Cruze
Department of Pharmaceutical Sciences, North South University, Plot # 15, Block # B, Bashundhara R/A, Dhaka 1229, Bangladesh.
Md. Ashikur Rahman
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Ishrat Jahan
Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh.
Mafruha Kumkum
Molecular Pharmacology and Herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Raisa Sharmili Habib
Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Md. Rafat Tahsin *
Department of Pharmaceutical Sciences, North South University, Plot # 15, Block # B, Bashundhara R/A, Dhaka 1229, Bangladesh.
Fahima Aktar
Molecular Pharmacology and Herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Tahmina Aktar
Department of Physiology, Dhaka Medical College, Dhaka, Bangladesh.
Jakir Ahmed Chowdhury
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Shaila Kabir
Molecular Pharmacology and Herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Abu Asad Chowdhury
Molecular Pharmacology and Herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Md. Shah Amran
Molecular Pharmacology and Herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Because of the short comings of conventional anti-inflammatory drugs, the researchers have driven their attention towards natural products. Medicinal plants have got acknowledged for greatly impacting on the health of individuals and communities. Spondias mombin is a great species, traditionally used for several medicative objectives from ancient times. It has also been popular for it’s analgesic and anti-inflammatory effect. In this study, we an effort was made to evaluate the analgesic and anti-inflammatory effect of Spondias mombin against the conventional drugs. the plant extract from different region was induced through intraperitoneal route and the efficiency was compared with paracetamol and ibuprofen. It was seen that both the conventional drug and extract of Spondias mombin significantly reduce the inflammation. The plant extract has also shown effects irrespective of geographical interest. Hence it might be assumed that Spondias mombin could be a suitable alternative therapy in reducing pain and inflammation and to surpass the side effects of ordinary conventional medicines.
Keywords: Anti-inflammatory, Spondias mombin, conventional, medicinal plants, analgesic